Leroy (Lee) Cronin
Professor, School of Chemistry
University of Glasgow (Scotland)
A Universal Approach to Reaction Informatics: Today it is possible to design and synthesize many of the physically allowed molecules and materials conceivable if practical, yet paradoxically it is not possible to reproduce or rerun these successful procedures with high reliability. This is because many of the conditions devised for the manual or semi-manual synthesis are not uniformly recorded and there is no standard way of recording reaction informatics. His group works on solving this problem by devising a universal approach to recording reaction informatics and chemical synthesis that allows them to translate all procedures, manual or automatic, to a new standard language for exploring chemical reactions and synthesis.
Furthermore, this new approach maps into a universal programming language for chemistry that is accessible to ALL synthetic chemists and will work on ALL robotic systems (subject to suitable specification), thus capable of universally turning code into reliable chemistry and materials processes.
J. Granda, L. Donina, V. Dragone, D. –L. Long, L. Cronin. Controlling an organic synthesis robot with machine learning to search for new reactivity. Nature, 2018, 559, 377-381.
S. Steiner, J. Wolf, S. Glatzel, A. Andreou, J. Granda, G. Keenan, T. Hinkley, G. Aragon-Camarasa, P. J. Kitson, D. Angelone, L. Cronin. Organic synthesis in a modular robotic system driven by a chemical programming language. Science, 2019, 363, 144-152.
] S. Hessam M. Mehr, M. Craven, A. Leonov, G. Keenan, L. Cronin. A universal system for digitization and automatic execution of the chemical synthesis literature. Science, 2020, 370, 101-108A.
D. Caramelli, J. M. Granda, S. Hessam M. Mehr, D. Cambié, A. B. Henson and L. Cronin. Reactivity First Approach to Autonomous Discovery of New Chemistry. ChemRxiv, Theoretical and Computational Chemistry, 2021.
Latest honors & awards
NIH Integrated Challenge Prize, JSCC International Award (both in 2019)
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